Cryotherapy

Medical Info

DermaFreeze is recommended for cryotherapy of various benign skin and mucosal lesions. It is composed of fluorinated gases, non-toxic, odourless, non-flammable and compatible with global environmental legislation.

DermaFreeze is effective for the controlled destruction of epidermal lesions. It freezes living tissue at -30°C. A white ‘frost’ forms on the treated skin. Bigger lesions can be frozen multiple times to achieve a deeper level of treatment. The healing process is the same as that of cryosurgery with liquid nitrogen. (Tissue is destroyed at around -15°C; Dermafreeze evaporates at -30°C; liquid nitrogen at -190°C causing a lot more tissue damage than is required.)

The lesion should be cleaned with an alcohol swab. Select an applicator that when pressed down, the lesion is clearly visible. Press down on the applicator to prevent spillage when freezing. The patient should be positioned so that the applicator cone is in an upright position. Insert the tube at about a 45° angle and press/pull the trigger gently until the product covers the lesion. Keep the applicator cone in position until the bubbling (boiling) stops and you see the frost icing over the lesion. Remove the applicator. The lesion will ‘thaw’. Repeat the process if necessary. Wear safety goggles and gloves for protection.

The keratinic tissue of plantar warts should be removed mechanically before freezing it with a longer spray of DermaFreeze® to achieve a deeper level of ‘damage’. Multiple applications can be used depending on the lesion.

A dark blister will form within a day. When the blister peels off, tender skin will be exposed. Clean with saline/salt water twice a day. A product like Fix or a silicone gel can be used on the lesion at this stage.

Disinfect applicators after use – it is safe to use detergent and broad-spectrum disinfectants and the applicators can be sterilised by blue light.

Store DermaFreeze® at room temperature in a well ventilated room. Do not expose it to direct sunlight or transport it in a hot vehicle – use a cooler box for safety when in transit

Keep away from children. Exposure to eyes can cause permanent damage.

The kit consists of one 200ml Dermafreeze unit + six funnel applicators of different sizes and one applicator tube. One can is generally enough for 80-120 applications. The different funnel sizes allows for a precise margin of normal skin around the lesion and limits damage to normal skin.

Lesions suitable for treatment:

• Warts including plantar, penile, vaginal warts
• Papillomata
• Molluscum contagiosum
• Skin tags
• Keratin 'horns'
• Pigmented lesions (actinic/solar keratosis)
• Small superficial BCC

Applications

Published Studies

South African Medical Codes

Why you should use DermaFreeze

We took over the sales of Dermafreeze from Dr Jens Pieper when he retired because it is just a great product. I have been using it in my practice for the past four years. Dermafreeze does not use sponge tipped applicators which I found imprecise and wasteful. The funnel applicators have precise margins and you use the minimum amount of liquid freezing agent.

For very superficial lesions a single controlled application is enough. For bigger lesions or skin tags I often apply a second spray at the same time. Only a very stubborn plantar wart needed treatment on more than one occasion.

I work in a small town and liquid nitrogen is not freely available. Dermafreeze does not dissipate like nitrogen and it is stable on your shelf for about three years after opening it. The product developer is trying to get it registered as used ‘to the last drop’ in his country.

I have two sets of funnels – one used for warts and the other set for other lesions.

I have used Dermafreeze on oral mucosa for juvenile/flat warts with success. I have not used it on vaginal mucosa yet though the developer’s website states that it is safe to use vaginally.

Even diabetic patients do well after treatment. I have not had any complications and I use it extensively on facial lesions.

Obviously big lesions use more product than small lesions and generally I charge a/t the number of ‘sprays’ and not necessarily the number of lesions. I tend to be bad at business and better at medicine and have not worked out exactly what my profit margin is but a quick calculation – I make at least double to three times what I paid for my Dermafreeze over the last three years making it economically viable.

I like prescribing Fix wound spray to use once the blister peels off. Patients are advised to clean the wound with gauze and salt water/saline and to apply Fix directly after. Once healed I advise Adco-Kelocote bd for three months for bigger lesions, though some practitioners prefer silicone gel.

Dr Liezl Stockigt
MBChB (UOVS) DOH (UCT) Aesthetic Practice

Keratinic Horn - day 1 / day 10

Keratinic Horn - day 1 / day 10

Skintag - day 1 / day 10

Solar Keratosis - day 1 / day 10

Solar Keratosis - day 1 / day 10

DermaFreeze usage instructions

Applications and how to use

DermaFreeze is recommended for cryotherapy of various benign skin and mucosal lesions. It is composed of fluorinated gases, non-toxic, odourless, non-flammable and compatible with global environmental legislation.
DermaFreeze is effective for the controlled destruction of epidermal lesions. It freezes living tissue at -30°C. A white ‘frost’ forms on the treated skin. Bigger lesions can be frozen multiple times to achieve a deeper level of treatment. The healing process is the same as that of cryosurgery with liquid nitrogen. (Tissue is destroyed at around -15°C; Dermafreeze evaporates at -30°C; liquid nitrogen at -190°C causing a lot more tissue damage than is required.)
The blue tag – remove the tag that covers the trigger (Video above refers). Insert the extender tube and test gas flow. Wear safety goggles and gloves for protection.
The lesion should be cleaned with an alcohol swab. Select an applicator that when pressed down, the lesion is clearly visible. Press down on the applicator to prevent spillage when freezing. The patient should be positioned so that the applicator cone is in an upright position. Insert the tube at about a 45° angle and press/pull the trigger gently until the product covers the lesion. Keep the applicator cone in position until the bubbling (boiling) stops and you see the frost icing over the lesion. Remove the applicator. The lesion will ‘thaw’. Repeat the process if necessary.
The keratinic tissue of plantar warts should be removed mechanically before freezing it with a longer spray of DermaFreeze® to achieve a deeper level of ‘damage’. Multiple applications can be used depending on the lesion.
A dark blister will form within a day. When the blister peels off, tender skin will be exposed. Clean with saline/salt water twice a day. A product like Fix or a silicone gel can be used on the lesion at this stage.
Disinfect applicators after use – it is safe to use detergent and broad-spectrum disinfectants and the applicators can be sterilised by blue light.
Store DermaFreeze® at room temperature in a well ventilated room. Do not expose it to direct sunlight or transport it in a hot vehicle – use a cooler box for safety when in transit.
Keep away from children - Exposure to eyes can cause permanent damage.
Product can be used for up to three years after opening.
Can and applicators are recyclable.
Product registration – Brazilian Agency of Health surveillance #80409950001.
Especially recommended for use in medical/veterinary practices where access to liquid nitrogen is limited.

Online Orders

Online-orders can be placed via e-mail at orders@dermafreeze.co.za

How to contact us

E-mail and WhatsApp is preferred for communication during office hours.

Dr. LG Stockigt Inc.
33 Voortrekker Street
Beaufort West
6970 - RSA

T: 023 415 2663
C: 082 786 8445
e-mail: orders@dermafreeze.co.za